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age-related changes in the glutathione redox system Brain Disorders and Aging 1: The role of the
Description
Investigations have revealed that the orphan nuclear receptor NR4A1 is pivotal in mediating metformins protective effects against endothelial dysfunction induced by high glucose levels

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6d, Table 1)

Given the extensive evidence linking redox dysfunction to ALS, it is not surprising that several redox-active molecules have been trialed as potential therapeutic agents
