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Patients experiencing significant gastrointestinal side effects may benefit from temporary dose reduction or slowing the titration schedule

doi: 10.1210/jc.2006-2003

Collagen is essential for wound healing, maintaining healthy skin, and supporting the structure and integrity of various body tissues
The phenotypic outcome is a shift toward higher energy expenditure and improved adipose/lipid profiles without the catabolic loss of lean tissue commonly seen with severe caloric restriction
