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The phenolic hydroxyl group (-OH) in guaiacol undergoes deprotonation, losing a hydrogen ion (H + ) to form a phenolate anion (-O )

Eur J Pharmacol 861:172593 Luetic K, Sucic M, Vlainic J, Halle ZB, Strinic D, Vidovic T et al (2017) Cyclophosphamide induced stomach and duodenal lesions as a NO-system disturbance in rats: L-NAME, L-arginine, stable gastric pentadecapeptide BPC 157

350,351 Clinical trials in older women have similarly reported finding improved bone turnover marker levels after six to 12 months of prune consumption

Effect of probiotics supplementation on heart rate: a systematic review and meta-analysis of randomized clinical trials