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The search was conducted on human studies, but it was not limited to title and abstract because our desired results or outcomes might have been considered a secondary aim of the studies and mentioned in the full text of articles

New approach for bone marrow transplantation in patients with class 3 thalassemia aged younger than 17 years

Among various indicators, glutathione reductase (GR), a key enzyme in the oxidative stress process, shows activity changes that can signal hepatocyte metabolic stress and functional abnormalities earlier, providing an important diagnostic window for identifying early liver damage [3]

[DOI] [PubMed] [Google Scholar] 4.O'Rourke B, Ramza BM, Marban E