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Gating residues involved in the occluded-to-inward conformational transition of OCTN2 Alternating-access transport by secondary active transporters requires the coordination of gates that enclose or preclude access to the substrate-binding site from either side of the membrane 51

The glial scar plays a dual role in the pathological process after SCI and other CNS injuries: both protective and inhibitory (12, 13)
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Competing interests The authors declare that they have no financial and non-financial conflict of interest