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The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Initiative: methods of the EGAPP Working Group
doi: 10.1089/ars.2020.8212

Pyruvate maintains energy supply and intracellular redox potential for oocytes, promotes the maturation of oocyte nucleus and cytoplasm, inhibits oocyte aging, and affects oocyte transcriptional activity and lipid metabolism through the formation of acetyl-CoA [39, 139,140,141,142,143,144,145,146,147,148,149,150, 155, 156]

The activation of the PI3K/Akt/mTOR signaling pathway is crucial during immune cell activation
