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Oct 2015;25(10):779-84 e1

Several studies have pointed out that ASD subjects of all ages present nutritional abnormalities and redox imbalances caused by the dysfunctional mitochondria ( Several studies have proposed that ASD may involve different biological profiles, including alterations in redox balance, mitochondrial dysfunction and immune-inflammatory signaling

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WISP1 can be influenced by increased weight in humans, becomes elevated with insulin resistance in children and adolescents (616, 631), and is elevated during gestational DM (632)