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They significantly influence growth, development, and physiological processes
[DOI] [PubMed] [Google Scholar] 8.Starkie RL, Rolland J, Angus DJ, Anderson MJ, Febbraio MA

In insulin-resistant states, the liver continues to promote lipid synthesis but fails to suppress glucose production

However, another study suggests that the inhibitory function of PAI-1 on HSC mobilization is solely attributed to intracellular PAI-1 activity based on transwell migration assays and cell transplantation studies (547)
