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The last NAC administration was given 2.5 h prior the behavioral experiments, as it has been demonstrated that glutamate levels were elevated in the rat brain approximately 2.5 h after NAC administration (48)

doi: 10.1016/j.autrev.2014.01.007 5 JonklaasJBiancoACBauerAJBurmanKDCappolaARSawkaAMet al
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Iron oxide/manganese oxide co-loaded hybrid nanogels as pH-responsive magnetic resonance contrast agents
