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The noradrenergic locus coeruleusnorepinephrine (LC-NA) system, which is among the earliest brain regions affected in NDDs, including AD and PD, represents a crucial therapeutic target for these conditions (86, 87)

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We found that treatment significantly increased the plasma concentration of glycine and enhanced the urinary excretion of isobutyrylglycine, tigylglycine, isovalerylglycine, and hexanoylglycine

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