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Stimulation of dermal fibroblast proliferation was chosen to verify activity of engineered PDGF-BB, while the activity of engineered IL-1Ra was verified by measuring its capacity to inhibit IL-6 release by macrophages in response to IL-1
A phase II human trial was initiated for ulcerative colitis, with encouraging preliminary results

For both men and women , compared with having two children, having no children or four or more were apparently associated with greater risk of dementia

doi: 10.1002/cncr.28031
