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Clin Exp Pharmacol Physiol20073452832

Additional data also documented an association between BDNF and cognitive decline in PD patients, and it was hypothesized that a reduction in BDNF was associated with cognitive decline in PD patients (Wang Y

It also exhibited low CYP inhibitory promiscuity and was predicted to be non-AMES toxic, non-carcinogenic, and non-inhibitor of the hERG gene

Furthermore, the prevalence and intensity of HSN in PIGD patients have been associated with more severe motor dysfunctions and a faster disease progression, underscoring the clinical relevance of TCS as a diagnostic and prognostic tool (54)