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-Carrageenan exhibits antiviral properties, making it a candidate for nasal sprays, but its limited spray coverage and poor mucoadhesion restrict its effectiveness 26

In particular, it demonstrates that polymer nanoparticles with tailored physicochemical properties, such as size, shape, and surface charge, can efficiently cross the BBB

Antigen-specific T cells generally reside in TAM-rich regions of the TME and T cell-TAM interactions contribute to T cell exhaustion programs or prevent TIL infiltration into the tumor nests 242, 243, 244 In contrast, cDCs, although more rare, are a prognostic marker and correlate with the number of stem-like Texh-prog cells 60, 245, 246