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Leukemia (2020) 34(1):7586
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Moreover, Pol3 and the Fe/S biosynthetic genes are synthetic lethal, indicate that ISC is an essential cofactor for DNA polymerase to regulate its structure and functions ( IronSulfur (Fe/S) Clusters Protein and DNA Repair Oxidation, deamination, and alkylation are likely to induce single base damage in DNA
