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The age at start of treatment ranged between 4.7 years and 16 years, 11.9 3.3 years for the 68 males and 12 1.9 years for the 20 females

This observation has led to an intriguing hypothesis that SelC binding to the SECIS motif has dual effect in eukaryotes, resulting in the recoding of the UGA codon and stabilization of the mRNA in a selenium-dependent manner (18)

Abstract The intestine is the largest interface between the internal body and the external environment

This inability to maintain immunological homeostasis in the gut encourages the entry of luminal antigens into underlying tissues where excessive inflammatory responses are induced further (Knig et al