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Given that the accumulation of intracellular iron not only is crucial for TFH cell differentiation but can also induce ferroptosis, whether the balance between these two factors can be modulated to improve TFH cell immune imbalance has attracted increasing attention (148)
doi: 10.1038/sj.jid.5700338
Furthermore, ACSL4 expression levels correlate positively with periodontal PD and CAL ( 2.3 Collapse of the antioxidant defense system and pathogenic regulation Cellular survival relies on a multi-layered antioxidant defense system
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