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Description
E.PardoL
ALA is able to trigger Akt phosphorylation in human umbilical vascular endothelial cells and in THP-1 human monocyte cell lines [84,85]
In particular, using an allelic series of Col4a1 mutations, Jeanne and colleagues nicely demonstrated that the severity of the hemorrhagic phenotype was modulated by the position of the mutation, environmental factors (such as exercise) and the genetic background, findings which perfectly align with observations in patients (427)
HRP, horseradish peroxidase
