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Description
in this pathway, IL-6 binds to sIL-6R to form IL-6-sIL-6R complexes
IL-13R2 is not believed to contribute to IL-13 signaling since it possesses a short cytoplasmic tail without signaling motifs [45]
Mutations in Parkin or PINK1 impair these proteins, leading to the accumulation of damaged mitochondria, reduced energy production, and elevated levels of reactive oxygen species (ROS) 39
[PMC free article: PMC4532752] [PubMed: 26268692] 624
