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VGF is a member of the granin family, and the coordination among its family members plays a crucial role in the biogenesis of secretory granules 22
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However, insulin sensitivity and glucose tolerance were maintained, likely owing to an increased conversion of saturated fatty acids (known to cause insulin resistance) to monounsaturated fatty acids mediated by stearoyl-CoA desaturase-1 (SCD1) [52]
A: Skin cell turnover occurs approximately every 28 days, meaning visible improvement in pigmentation requires at least one full cycle
