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BPC-157 significantly enhances ERK1/2 phosphorylation in a dose-dependent manner, activating downstream targets including transcription factors c-Fos, c-Jun, and Egr-1
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Simultaneously, long-chain acyl-CoA synthetase 4 (ACSL4) expression decreases, reducing the availability of oxidizable PUFAs, although the exact mechanism underlying this remains unclear
