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In early T cell activation, the increase in intracellular calcium can activate AMPK, limiting mTOR signaling and precluding the activation of downstream mediators and premature engagement of the glycolytic anabolic metabolism associated with the proliferative phase of clonal expansion (59)
Biofilms are communities of microorganisms encased in a protective layer that makes them more resistant to antibiotic treatment

Decreased production of and response to interleukin-2 by cultured lymphocytes from patients with systemic lupus erythematosus

doi: 10.1056/NEJM195307022490104 7 AnandBKChhinaGSSharmaKNDuaSSinghB
