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It is administered using topical creams, intravenously, or co-administered with a facial treatment

Because of ubiquitination and subsequent proteolysis, Nrf2 turns over rapidly with a half-life of 715 min, which increases to 30100 min in the presence of oxidative or electrophilic stress (McMahon et al

The most commonly reported effects are mild and transient: slight headache or nasal irritation with intranasal use, and minor injection site sensitivity with the subcutaneous route

It has the ability to prevent damage from reactive oxygen species (ROS), free radicals, peroxides, lipid peroxides and heavy metals to cells