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Interestingly, Ox-LDPE-MPs showed greater inflammatory responses and intestinal damage compared to LDPE-MPs which was hypothesized to result from their easier cellular accumulation (Wang et al., 2023b)
This has driven the development of specific STING agonists, such as cyclic dinucleotide (CDN) analogues ADU-S100 and MK-1454, as well as the non-CDN small molecule GSK-3745417

Physiologically, inactive NF-B interacts with cytoplasmic inhibitor protein IkappaB (IB)

Starch and albumin mixture as replacement fluid in therapeutic plasma exchange is safe and effective
