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because reactive oxygen species are a major trigger for mast cell instability, lycopene's ability to quench singlet oxygen removes one of the primary irritants provoking the mast cells

doi: 10.1289/EHP6785 19

Specifically, HNE reportedly directly activates two members of the stress-activated kinase family, JNK and p38, in NT2 neuronal cells (198)

Science Bulletin