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Description
When joints are inflamed, they produce excess reactive oxygen species (ROS), which include superoxide and hydrogen peroxide, to the point that they overwhelm the bodys defences and deplete the local glutathione supply [6]
Recently the lipid peroxidation product 4-HNE was shown to directly adduct GCLC Cys553 (and GCLM Cys35) in vitro [132]
Registered General Nurse (1996) with extensive background of experience within GP Practice and Urgent Care settings
I.LeonhardtB
