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To determine whether variants in novel genes contribute to this disorder, we evaluated TMA metabolism by choline challenge, conducted a sensory evaluation and sequenced the exome of ten subjects with complaint of TMA-related body odor

When administered for long periods, several well-known hepatic enzyme inducers are associated with development of liver neoplasia (Butler 1996

TP53 germline mutations Germline mutation of TP53 in the heterozygous LOF form usually presents with a rare autosomally dominant genetic disease with a significantly increased risk of cancer development known as Li-Fraumeni syndrome (LFS)