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They increase blood flow, release growth factors, activate stem cells, and reduce inflammation

Courtois, M., Loussouarn, G., Hourseau, C., & Grollier, J

BDNF release from single cells elicits local dendritic growth in nearby neurons

Gastrointestinal symptoms: alteration in bowel motility, such as mild diarrhea or constipation, and loss of bladder or bowel control