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Their analyses reported that GHK's signature was associated with expression changes across a large number of human genes, including genes related to extracellular-matrix homeostasis, inflammation, and DNA repair, and they framed these associations as consistent with a broad, multi-gene profile rather than a single-pathway effect [4]

doi: 10.3748/wjg.v20.i1.6 [DOI] [PMC free article] [PubMed] [Google Scholar] 76

Notably, the capsidiol-related cluster was found to be conserved in Nicotiana sylvestris , Nicotiana tomentosiformis , and Nicotiana attenuata (Chen et al

Each biological sample was therefore measured once, without technical replicates