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Triptolide, for instance, significantly ameliorates NAFLD through a dual regulatory mechanism: on one hand, it enhances the phosphorylation of AMPK and ACC1 (increased by 2.1-fold and 1.8-fold, respectively), thereby suppressing key lipogenic factors such as SREBP-1 (42%) and SCD-1 (39%)

[DOI] [PubMed] 51.Burde R, Schainker B, Kayes J

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