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In heart failure, ANT1 deficiency impairs mitophagy, leading to accumulation of dysfunctional mitochondria and exacerbating energy deficit

PLoS ONE 11 , e0165047 (2016)

However, a possible confounding factor is that ribose models tend to use a supraphysiological ribose concentration, which may induce an excessive AGE crosslinking profile

doi: 10.1016/j.yexmp.2021.104605, 242 ZhangL.DuZ.HeL.LiangW.LiuK.GongS
