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Description
Untargeted lipidomics analysis of synovial fluid and serum from RA patients across various clinical stages, ranging from preclinical to active and sustained phases, showed that despite normal erythrocyte sedimentation rate and CRP at pre-clinical stages, the lipidomic profile of preclinical RA joint fluid closely resembled that of active RA (191)

Introduction of mutations is largely random, as such, this approach is typically combined with high-throughput screening, which can be both time and resource- consuming

if adverse reactions occur, discontinue use

Kikuchi, T
