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Clinical evaluation can later be expanded to other target drug metabolizing enzymes and transporters using larger probe cocktails (five to six object drugs), which may reveal other drug interactions that were either not tested or missed in vitro (Nguyen et al., 2021)

Such activities can be classified as intrinsic resistance mechanisms

[DOI] [PMC free article] [PubMed] [Google Scholar] Diederich M., Wellman M., Visvikis A., Puga A., Siest G

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