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These events collectively result in mitochondrial dysfunction, elevated ROS, and impaired protein clearance, the triad that drives S misfolding and aggregation

Thus, circadian genes and genes related to tissue deterioration can also form positive feedback loops to maintain tissue homeostasis

By targeting specific microbial populations, EOs can inhibit methanogenic archaea and hyper ammonia-producing bacteria, thereby reducing methane emissions and ammonia concentrations while promoting a fermentation pattern that favors the production of propionate and butyrate, VFAs crucial for energy metabolism [97, 98]

JAGS 56(5):831-839