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A summary of the studies conducted on cobalamin and its role in MS is given in Table 1

Vitamin B12 status and rate of brain volume loss in community-dwelling elderly

The metabolism and clearance of both components may be affected by significant liver disease, and patients with severe hepatic impairment should be monitored closely if treatment is deemed necessary

The Bayley-III is considered to be the gold standard in developmental assessment of this age group, and is widely used for research purposes worldwide
