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Description
Mutations in LRRK2 impair its function and disrupt the formation of aggressive aggregates (aggresomes) that normally facilitate the autophagic clearance of protein aggregates (Stefanis et al., 2019)

Many people feel tired as they get older

Crocetti, D

Genetic models (for example ob/ob and foz/foz mice) add obesity and metabolic derangement
