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The corresponding pharmacokinetic parameters that were derived from the compartmental and non-compartmental analyses are shown in Table 1 and Supplementary Table S1, respectively

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The primary research work by the authors on the topic of this review is supported by NIH grants R35-CA252978 (JM), P01-CA129243 (JM), R01-HL145037 (DS) and R01-HL142568 (DS), P30-CA008748 (MSKCC), and by the Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center at MSKCC Footnotes Declaration of Interests Joan Massagu holds company stock of Scholar Rock, Inc