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DNA methylation in recognition sequences of some TFs was revealed to alter their binding specificity (Zhu et al., 2016)
After entering the RBC, glucose is immediately converted to glucose-6-phosphate by hexokinase (HK) and then fueled into the glycolytic pathway or into the PPP [182]

Chemotherapy-induced thrombocytopenia is the most common type of DIT that follows this mechanism

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