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Taken together, these data suggest that inflammatory status is improved in skeletal muscle in Cpt1b m/ mice despite the presence of excess lipids at the systemic and tissue levels
Its characterized by: excessive hair growth (hypertrichosis), papery thin and fragile (atrophic) skin, outward turned eyelids (ectropion) and a large mouth (macrostomia)
Gradual titration is essential: Opening at 2 mg weekly instead of a higher dose markedly lowers the odds of early gastrointestinal effects [4]
