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Lastly, epithalon plays a significant role in the endocrine system by increasing levels of endogenous hormones that naturally diminish with age, such as melatonin (which helps regulate the sleep cycle), and gonadotropic hormones (FSG, LG, prolactin), which play a role in reproductive functions [8]

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This multi-modal strategy costs less than repeated professional-only treatments producing superior long-term outcomes versus topical-only protocols potentially producing incomplete results in moderate to severe cases