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The clinical reality is much narrower than the marketing

In 2023, the FDA classified it as a Category 2 bulk drug substance , meaning it cannot be legally compounded by commercial pharmaceutical compounding pharmacies in the United States

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Bruising is more likely if: A needle is too large The injection angle is off The needle is pulled out too quickly The injection is done too fast There is less fat under the skin, which means less padding Certain medications or supplements are being used, such as blood thinners, fish oil, or vitamin E How to prevent bruising Use a 29 to 31 gauge insulin syringe with a 4 to 8 millimeter needle