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The metabolic alterations in tumors encompass all stages of cellular-metabolite interactions [6]

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Furthermore, in numerous cancers, including lymphoma, colorectal cancer, pancreatic cancer, and breast cancer, treatment strategies combining DFMO with other polyamine transport inhibitors, such as AMXT 1501 and Trimer PTI, are more effective at inhibiting cancer cell proliferation and enhancing anticancer effects than monotherapy [299,300,301]

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