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Drossman DA, Dumitrascu DL: Rome III: New standard for functional gastrointestinal disorders

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These phenotypic changes occur without alteration of the NADP + /NADPH ratio but with accumulation of the terminal oxPPP product (and non-oxPPP substrate) ribose 5-phosphate as well with decreased levels of glycolytic metabolites, possibly due to impaired pentose overflow 135

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Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP-ribose) polymerase activation

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