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The -oxidation is normally responsible for only a small component of VPA metabolism (Fig
Fusco R, Siracusa R, Genovese T, Cuzzocrea S, Di Paola R

Gut microbiota-derived metabolites in the regulation of host immune responses and immune-related inflammatory diseases

Finally, emerging studies have begun to investigate whether specific miRNAs or epigenetic modulators could regulate key enzymes and inflammatory pathways involved in TMAO metabolism [32, 33], although this remains largely experimental
