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10.4149/gpb_2013027 [DOI] [PubMed] [Google Scholar] Walsh ME, Shi Y, Van Remmen H (2014) The effects of dietary restriction on oxidative stress in rodents free

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Taking quercetin as an example, its copper-complexed form (CuQ) not only exhibits superior antioxidant activity compared to free quercetin but can also switch to a pro-oxidant state in the tumor microenvironment [256], inducing mitochondrial oxidative damage and DNA strand breaks