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Psychiatric Disorders:depression, sleep disorders (including insomnia and nightmares) Reproductive System and Breast Disorders:gynecomastia Respiratory Disorders:interstitial lung disease Skin and Subcutaneous Tissue Disorders:drug reaction with eosinophilia and systemic symptoms (DRESS), lichenoid drug eruption Rosuvastatin is a substrate of CYP2C9 and transporters (such as OATP1B1, BCRP)

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The Caughey and Prusiner labs had both discovered that PIPLC, an enzyme that can cleave GPI anchors, would release PrP C , but not proteinase K-resistant PrP Sc , from the surface of prion-infected cells, thus implying that whereas PrP C could be found on the cell surface, PrP Sc was buried somewhere inside the cell [Caughey 1990, Borchelt 1990, Taraboulos 1990]

[DOI] [PubMed] [Google Scholar] 9.Chamomile: a herbal medicine of the past with bright future