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PPAR, on the other hand, regulates adipocyte differentiation and inflammatory responses, and IF reduces the generation of inflammatory factors by modulating PPAR activity (74, 75)

PMID: 17389505

Cytokines like tumor necrosis factor (TNF) are the main means by which these activated cells foster a chronic inflammatory state and impact processes like neo-angiogenesis, epidermal hyperproliferation, differentiation, and apoptosis

The expression of IL-1, IL-8, and keratin 16 in the herbal extract group was significantly decreased (Yang et al., 2021)
