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By decoupling cargo recognition from the capsids intrinsic sequence requirements, the aptamerABP interface functions as a universal adapter, achieving Loading Specificity that is virtually independent of the viral scaffolds native biology

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To generalize this approach to polyprotic acids with coupled sites of (de)protonation, typical in complex drug-like molecules, we reformulate this expression in terms of the "neutral fraction" , the fraction of total material which is in a neutral microstate (i.e

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