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Used together with atropine to treat poisoning caused by organophosphate cholinesterase inhibitors 2-PAM is not effective against the chemically different carbamate type cholinesterase inhibitors (such as neostigmine and pyridostigmine) because carbamates do not have phosphate groups and do not undergo aging

95 , 96 Though there is a dearth of clinical evidence, the pre-clinical models indicate an optimistic outlook

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As examples, it can be found two marketed eye drop formulations, including CDs: antibiotic clorocil (MB-CD/chloramphenicol) and the anti-inflammatory Voltaren ophthalmic (HP--CD/diclofenac sodium IC) under several brand names [27], Table 4