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The differential diagnosis should include a variety of benign and malignant conditions such as subungual hematoma, paronychia, pyogenic granuloma, subungual nevus, subungual fibroma, subungual verruca, keratoacanthoma, Bowen's disease, subungual squamous cell carcinoma, etc5, 9

Similar proportions of skin cancer diagnoses were observed in a Nigerian population, with 62% of dermatological malignancies diagnosed as SCC, 16% as melanoma, and 8% as BCC.[20] Of note, some melanomas found in individuals with albinism do contain melanin.[80] SCC occurring at extremely early ages is a hallmark of oculocutaneous albinism

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The average age is before the end of the first year of life 4 , 5 , 15 and the preferred anatomical sites are the cranio- maxillo-facial skeleton: midline maxillary bone (68%-80%), skull (10.8%), mandible (5.4%) as the case described in the present clinical case, in which the premaxilla and left maxillary portion were affected, extending to the floor of the nostrils