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Few studies have observed performance benefits as a result of supplementing with specific dietary antioxidants [37] and many well controlled studies in this area have found no performance benefit [2123, 3942]

For fatty liver disease itself , NICE guideline NG49 recommends risk stratification in primary care using the FIB-4 score initially, followed by the Enhanced Liver Fibrosis (ELF) test if indicated, to identify patients at higher risk of advanced fibrosis who may require specialist referral

This approach is not widely used in adults, due to the high incidence of GVHD, transplant-related mortality and GR, but it may be used to treat children with class I/II -thalassemia safely, provided that ATG is given [100]